Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGAV | P06756 | 2/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | FABP1 | P07148 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 4/20 | 0.33 |
| ▸ | HTR7 | P34969 | 4/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773230 | 0.87 | ITGB3 (0.44) | ITGB3ITGAVITGB1ITGA5ITGA2B | |
| SCHEMBL6774218 | 0.83 | ITGB3 (0.47) | ITGB3ITGAVITGB1ITGA5F2 | |
| SCHEMBL6778678 | 0.77 | MEP1B (0.48) | ITGB3ITGAVITGB1ITGA5KAT6A | |
| SCHEMBL6775123 | 0.75 | ALDH1A1 (0.46) | ITGB3ITGAVF2HTR1AHTR7 | |
| SCHEMBL6771727 | 0.71 | ITGB1 (0.48) | ITGB3ITGAVITGB1ITGA5F2 | |
| SCHEMBL6773446 | 0.70 | ADAMTS4 (0.39) | ITGB3ITGAVMMP13MMP2 | |
| SCHEMBL6771102 | 0.69 | ITGB3 (0.53) | ITGB3ITGAVITGB1ITGA5F2 | |
| SCHEMBL6768513 | 0.67 | ITGB3 (0.56) | ITGB3ITGAVITGB1ITGA5F2 | |
| Trifluoroacetic Acid SCHEMBL6801502 | 0.67 | ITGB3 (0.49) | ITGB3ITGAVITGB1ITGA5F2 | |
| SCHEMBL5184113 | 0.67 | NPSR1 (0.55) | ITGB3ITGAVITGA2BMMP13KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6833366-B1 | Dihydrostilbene alkanoic acid derivatives | PHARMACIA CORPORATION | 2004-12-21 | — | — | US | disclosed |
| US-6720315-B2 | FOR INHIBITING BONE RESORPTION, PERIODONTAL DISEASE, OSTEOPOROSIS, HUMORAL HYPERCALCEMIA OF MALIGNANCY, PAGET'S DISEASE, TUMOR METASTASIS, SOLID TUMOR GROWTH, ANGIOGENESIS, MACULAR DEGENERATION AND DIABETIC RETINOPATHY RETINOPATHY | PHARMACIA CORPORATION | 2004-04-13 | — | — | US | disclosed |
| EP-1289959-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | Pharmacia Corporation (US) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001096310-A1 | DIHYDROSTILBENE ALKANOIC ACID DERIVATIVES USEFUL AS VITRONECTIN ANTAGONISTS | PHARMACIA CORPORATION (US) | 2001-12-20 | — | — | WO | disclosed |