Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69183 | 0.77 | CLK1 (0.36) | POLBALDH1A1HPGDHTR1ATSHR | |
| SCHEMBL1400663 | 0.76 | CLK1 (0.40) | POLBALDH1A1HPGDHTR1ATSHR | |
| SCHEMBL12987971 | 0.75 | ALDH1A1 (0.39) | POLBALDH1A1HPGDHTR1ATSHR | |
| SCHEMBL12541476 | 0.75 | ALDH1A1 (0.44) | POLBALDH1A1CTSKTSHRSMN1; SMN2 | |
| SCHEMBL27789848 | 0.74 | CLK1 (0.37) | ALDH1A1HPGDHTR1ATSHRCLK1 | |
| SCHEMBL24323574 | 0.74 | HTR7 (0.41) | HTR1ACTSKCLK1HTR7DRD2 | |
| SCHEMBL3511520 | 0.74 | FAAH (0.36) | ALDH1A1HPGDMEN1KMT2AGRM5 | |
| SCHEMBL67116 | 0.73 | MTNR1A (0.45) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30500249 | 0.73 | POLB (0.38) | POLBALDH1A1TSHRSMN1; SMN2MAPK1 | |
| SCHEMBL28525227 | 0.73 | POLB (0.38) | POLBALDH1A1TSHRSMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814871-B1 | COMPOUNDS THAT MODULATE PPARY TYPE RECEPTORS, AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2011-03-02 | — | — | EP | disclosed |