Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.50 |
| ▸ | SYK | P43405 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.44 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 2/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770161 | 0.93 | SYK (0.47) | RPS6KB1ROCK2SYKALDH1A1LMNA | |
| SCHEMBL6770452 | 0.91 | RPS6KB1 (0.51) | RPS6KB1ROCK2SYKLMNAMAPT | |
| SCHEMBL6611762 | 0.89 | SYK (0.49) | ROCK2SYKLMNAMAPTROCK1 | |
| SCHEMBL6766687 | 0.88 | RPS6KB1 (0.53) | RPS6KB1ROCK2SYKROCK1MAPK1 | |
| SCHEMBL6769085 | 0.85 | SYK (0.52) | ROCK2SYKROCK1MAPK1HTT | |
| SCHEMBL6769259 | 0.84 | ROCK1 (0.52) | RPS6KB1ROCK2SYKALDH1A1ROCK1 | |
| SCHEMBL6639550 | 0.83 | SYK (0.53) | RPS6KB1ROCK2SYKROCK1MAPK1 | |
| SCHEMBL6608523 | 0.83 | SYK (0.48) | RPS6KB1ROCK2SYKLMNAMAPT | |
| SCHEMBL6772093 | 0.83 | PDGFRA (0.57) | ROCK2SYKROCK1EGFRKDR | |
| SCHEMBL6769445 | 0.82 | HSD17B10 (0.46) | ALDH1A1LMNAHTTEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762189-B1 | HEPATITIS B VIRUS AND HUMAN IMMUNODEFICIENCY VIRUS ANTIPROLIFERATION AGENTS; REDUCED CHANCE OF TOXICITY, SIDE EFFECTS, AND DEVELOPMENT OF RESISTANT VIRAL STRAINS | DONG WHA PHARM. IND. CO., LTD. (KR) | 2004-07-13 | — | — | US | disclosed |