Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772485 | 0.94 | HSD17B10 (0.46) | HSD17B10EGFRERBB2MEN1KMT2A | |
| SCHEMBL6770452 | 0.84 | RPS6KB1 (0.51) | EGFRERBB2MEN1KMT2ALMNA | |
| SCHEMBL6769928 | 0.82 | RPS6KB1 (0.52) | EGFRERBB2MEN1KMT2AALDH1A1 | |
| SCHEMBL6611762 | 0.82 | SYK (0.49) | EGFRERBB2MEN1KMT2ALMNA | |
| SCHEMBL6766687 | 0.81 | RPS6KB1 (0.53) | EGFRERBB2HTT | |
| SCHEMBL7079281 | 0.80 | ALDH1A1 (0.51) | HSD17B10MEN1KMT2AALDH1A1CYP19A1 | |
| SCHEMBL6772093 | 0.80 | PDGFRA (0.57) | EGFR | |
| SCHEMBL6769259 | 0.80 | ROCK1 (0.52) | EGFRERBB2ALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL6769085 | 0.79 | SYK (0.52) | EGFRNPC1HTT | |
| SCHEMBL6769930 | 0.79 | LMNA (0.47) | EGFRERBB2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6762189-B1 | HEPATITIS B VIRUS AND HUMAN IMMUNODEFICIENCY VIRUS ANTIPROLIFERATION AGENTS; REDUCED CHANCE OF TOXICITY, SIDE EFFECTS, AND DEVELOPMENT OF RESISTANT VIRAL STRAINS | DONG WHA PHARM. IND. CO., LTD. (KR) | 2004-07-13 | — | — | US | disclosed |