SCHEMBL6770650

SCHEMBL6770650

COc1c(C(=O)O)ccc2c1CC(C)S2(=O)=O

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
MAPT P10636 1/20 0.39
POLB P06746 1/20 0.36
HSD17B10 Q99714 2/20 0.33
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.31
LCK P06239 1/20 0.31
FYN P06241 1/20 0.31
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6753121 0.83 TDP1 (0.37) TDP1MAPTPOLBHSD17B10ALDH1A1
SCHEMBL6893610 0.79 TSHR (0.35) POLBALDH1A1KDM4E
SCHEMBL6772585 0.74 TDP1 (0.41) TDP1MAPTPOLBHSD17B10ALDH1A1
SCHEMBL16346452 0.71 ERN1 (0.34) POLB
SCHEMBL1505827 0.70 TDP1 (0.61) TDP1MAPTPOLBHSD17B10ALDH1A1
Hydrochloric Acid SCHEMBL2202243 0.68 TDP1 (0.59) TDP1MAPTPOLBHSD17B10ALDH1A1
SCHEMBL24650375 0.68 ADRA1A (0.42) TDP1MAPTPOLBHSD17B10ALDH1A1
SCHEMBL8118574 0.68 ALDH1A1 (0.35) TDP1MAPTPOLBALDH1A1KDM4E
SCHEMBL6751241 0.68 TSHR (0.33) ALDH1A1KDM4E
Hydrochloric Acid SCHEMBL8118586 0.67 ALDH1A1 (0.34) TDP1MAPTPOLBALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756343-B1 CONTROLLING RICE PADDY FIELD WEEDS AT LOW DOSAGE DOSE; PLANT SAFENING IDEMITSU KOSAN CO., LTD. (JP) 2004-06-29 US disclosed
US-20040002425-A1 Triketone derivatives and herbicides IDEMITSU KOSAN CO., LTD. (JP) 2004-01-01 US disclosed
EP-1120413-A1 TRIKETONE DERIVATIVE AND HERBICIDE IDEMITSU KOSAN COMPANY LIMITED (JP) 2001-08-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040002425-A1 Triketone derivatives and herbicides SYMPK, STK36, STK32A TDP1 2228/4885MAPT 2107/4885POLB 1780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.