Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK2 | O43353 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6770366 | 0.87 | SRC (0.56) | SRCRAB9ASMN1; SMN2L3MBTL1CA1 | |
| SCHEMBL6772487 | 0.86 | SRC (0.53) | SRCSMN1; SMN2CA1ALDH1A1KDM4E | |
| SCHEMBL6167303 | 0.84 | ALDH1A1 (0.45) | SRCRAB9ASMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6766708 | 0.82 | RIPK2 (0.48) | RIPK2SRCRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6767112 | 0.82 | OPRM1 (0.58) | RIPK2SRCCA1OPRM1 | |
| SCHEMBL6771294 | 0.81 | SRC (0.49) | SRCRAB9ASMN1; SMN2L3MBTL1CA1 | |
| SCHEMBL6772956 | 0.81 | SRC (0.49) | SRCRAB9ASMN1; SMN2L3MBTL1CA1 | |
| SCHEMBL6769419 | 0.81 | SRC (0.47) | SRCRAB9ASMN1; SMN2L3MBTL1CA1 | |
| SCHEMBL6778055 | 0.80 | SRC (0.43) | RIPK2SRCRAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6777584 | 0.80 | ALDH1A1 (0.53) | SRCRAB9ASMN1; SMN2L3MBTL1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |