Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 2/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6771869 | 0.87 | RIPK2 (0.50) | SRCOPRM1BRD4RAB9ASMN1; SMN2 | |
| SCHEMBL6772956 | 0.87 | SRC (0.49) | SRCOPRM1BRD4RAB9ASMN1; SMN2 | |
| SCHEMBL6771294 | 0.87 | SRC (0.49) | SRCOPRM1BRD4RAB9ASMN1; SMN2 | |
| SCHEMBL6769828 | 0.85 | OPRM1 (0.67) | SRCOPRM1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL6777584 | 0.85 | ALDH1A1 (0.53) | SRCBRD4RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6769419 | 0.84 | SRC (0.47) | SRCOPRM1BRD4RAB9ASMN1; SMN2 | |
| SCHEMBL6162529 | 0.83 | OPRM1 (0.56) | SRCOPRM1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL6772954 | 0.81 | OPRM1 (0.78) | OPRM1 | |
| SCHEMBL6772063 | 0.81 | OPRM1 (0.48) | SRCOPRM1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL6778055 | 0.79 | SRC (0.43) | SRCOPRM1BRD4RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |