Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | DCLRE1A | Q6PJP8 | 1/20 | 0.40 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | ACLY | P53396 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215840 | 0.84 | ESR2 (0.52) | ESR2CYP1A2ERCC5FEN1DCLRE1A | |
| SCHEMBL27739733 | 0.82 | ESR2 (0.48) | ESR2CYP1A2ERCC5FEN1DCLRE1A | |
| SCHEMBL5160117 | 0.81 | DCLRE1A (0.43) | ESR2CYP1A2DCLRE1ADCLRE1BBACE1 | |
| SCHEMBL455298 | 0.80 | ESR2 (0.47) | ESR2CYP1A2ERCC5FEN1DCLRE1A | |
| SCHEMBL8540746 | 0.78 | ALDH1A1 (0.44) | ESR2CYP1A2DCLRE1ADCLRE1BSMN1; SMN2 | |
| SCHEMBL20696572 | 0.78 | ALDH1A1 (0.44) | ESR2CYP1A2DCLRE1ADCLRE1BSMN1; SMN2 | |
| SCHEMBL6772346 | 0.76 | GAA (0.42) | CYP1A2DCLRE1ADCLRE1BBACE1ALDH1A1 | |
| SCHEMBL27489870 | 0.76 | ERCC5 (0.43) | ESR2CYP1A2ERCC5FEN1DCLRE1A | |
| SCHEMBL7698653 | 0.74 | ESR2 (0.50) | ESR2CYP1A2ERCC5FEN1AHR | |
| SCHEMBL15832277 | 0.73 | CRHBP (0.47) | ESR2CYP1A2DCLRE1ADCLRE1BBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040167193-A1 | Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED | 2004-08-26 | — | — | US | disclosed |
| US-6762197-B2 | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-13 | — | — | US | disclosed |
| US-20030119670-A1 | Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-06-26 | — | — | US | disclosed |
| EP-1238975-A1 | DIFLUOROMETHYLTRIAZOLONE COMPOUNDS, USE OF THE SAME AND INTERMEDIATES FOR THE PRODUCTION THEREOF | Sumitomo Chemical Company, Limited (JP) | 2002-09-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167193-A1 | Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof | CYP51A1, DPM1, CYP1A1 | ESR2 3163/4885CYP1A2 40/4885ERCC5 4220/4885 |
| US-20030119670-A1 | Difluoromethyltriazolone compounds, use of the same and intermediates for the production thereof | CYP51A1, DPM1, CYP1A1 | ESR2 3163/4885CYP1A2 40/4885ERCC5 4220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.