Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | FES | P07332 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780200 | 0.95 | ALDH1A1 (0.50) | TP53BP1ALDH1A1POLBNAMPTHDAC3 | |
| SCHEMBL6772992 | 0.90 | HDAC3 (0.40) | ALDH1A1NAMPTHDAC3HDAC1RXFP1 | |
| SCHEMBL6772811 | 0.88 | ALDH1A1 (0.46) | TP53BP1ALDH1A1POLBEGFRNAMPT | |
| SCHEMBL6779684 | 0.85 | MCHR1 (0.50) | ALDH1A1NAMPTDRD2MEN1KMT2A | |
| SCHEMBL6773364 | 0.84 | RXFP1 (0.43) | ALDH1A1POLBHDAC3HDAC1RXFP1 | |
| SCHEMBL6773077 | 0.84 | MCHR1 (0.49) | NAMPTHDAC3GAA | |
| SCHEMBL6779944 | 0.83 | HDAC3 (0.48) | HDAC3HDAC1DRD2ADRA1ADRD3 | |
| SCHEMBL6773542 | 0.82 | TP53BP1 (0.48) | TP53BP1ALDH1A1POLBEGFRNAMPT | |
| SCHEMBL6774104 | 0.82 | POLB (0.44) | POLBHDAC3HDAC1ABL1BCR | |
| SCHEMBL6773275 | 0.81 | TRPV1 (0.43) | HDAC3HDAC1HDAC2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |