Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | DRD4 | P21917 | 6/20 | 0.43 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768556 | 0.90 | SMN1; SMN2 (0.49) | MAPTSMN1; SMN2NPC1TP53RAB9A | |
| SCHEMBL6773544 | 0.89 | TLR7 (0.51) | TLR7TLR8 | |
| SCHEMBL6768596 | 0.89 | MCHR1 (0.47) | GAAMCHR1TLR7TLR8NAMPT | |
| SCHEMBL6772850 | 0.88 | TLR7 (0.44) | TLR7TLR8DRD2DRD3 | |
| SCHEMBL6779684 | 0.88 | MCHR1 (0.50) | GAAMAPTMCHR1SMN1; SMN2NPC1 | |
| SCHEMBL6772811 | 0.87 | ALDH1A1 (0.46) | MAPTTLR7TLR8DRD2NAMPT | |
| SCHEMBL6777586 | 0.87 | PKM (0.47) | MAPTNPC1HTTRAB9AHSD17B10 | |
| SCHEMBL6768616 | 0.85 | MCHR1 (0.47) | GAAMAPTMCHR1SMN1; SMN2NPC1 | |
| SCHEMBL6771963 | 0.85 | MAPT (0.46) | GAAMAPTMCHR1SMN1; SMN2NPC1 | |
| SCHEMBL1312806 | 0.84 | TLR7 (0.51) | GAAMAPTSMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |