Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20707259 | 1.00 | HDAC1 (0.53) | HDAC1HDAC7ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6779279 | 0.98 | TDP1 (0.54) | HDAC1HDAC7ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL6778346 | 0.98 | TDP1 (0.54) | HDAC1HDAC7ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL751414 | 0.95 | ALDH1A1 (0.54) | HDAC1HDAC7ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL368756 | 0.88 | ALDH1A1 (0.65) | ALDH1A1RAB9ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL10673491 | 0.86 | TDP1 (0.54) | HDAC1HDAC7ALDH1A1TDP1L3MBTL1 | |
| SCHEMBL16392601 | 0.82 | ACHE (0.60) | MAOB | |
| SCHEMBL8019454 | 0.82 | KMT2A (0.53) | HDAC1HDAC7ALDH1A1HDAC8HDAC3 | |
| SCHEMBL17280821 | 0.82 | MAOB (0.56) | HDAC1HDAC7MAOBMEN1KMT2A | |
| SCHEMBL17267477 | 0.81 | HDAC7 (0.64) | HDAC1HDAC7ALDH1A1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3438155-B1 | BIODEGRADABLE HYDROGEL HAVING CYCLIC BENZYLIDENE ACETAL STRUCTURE | NOF CORP (JP) | 2023-09-06 | — | — | EP | disclosed |
| US-11529423-B2 | Biodegradable polyethylene glycol derivative having cyclic benzylidene acetal linker | NOF CORPORATION (JP) | 2022-12-20 | — | — | US | disclosed |
| US-11530295-B2 | Hydrophilic polymer derivative having cyclic benzylidene acetal linker | NOF CORPORATION (JP) | 2022-12-20 | — | — | US | disclosed |
| US-11041052-B2 | Biodegradable hydrogel having cyclic benzylidene acetal structure | NOF CORPORATION (JP) | 2021-06-22 | — | — | US | disclosed |
| EP-3130587-B1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORP (JP) | 2021-06-16 | — | — | EP | disclosed |
| EP-3357514-B1 | LIPID DERIVATIVE IN WHICH HYDROPHILIC POLYMER IS BOUND VIA CYCLIC BENZYLIDENE ACETAL LINKERS | NOF CORP (JP) | 2021-04-14 | — | — | EP | disclosed |
| EP-3279236-B1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORP (JP) | 2021-01-06 | — | — | EP | disclosed |
| US-10808050-B2 | Antibody-drug conjugate having cyclic benzylidene acetal linker | NOF CORPORATION (JP) | 2020-10-20 | — | — | US | disclosed |
| US-20200291178-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2020-09-17 | — | — | US | disclosed |
| US-20200289656-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2020-09-17 | — | — | US | disclosed |
| US-20170290919-A1 | ANTIBODY-DRUG CONJUGATE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2017-10-12 | — | — | US | disclosed |
| US-20170107325-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170107325-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF CORPORATION (JP) | 2017-04-20 | — | — | US | disclosed |
| EP-3130587-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | NOF Corporation (JP) | 2017-02-15 | — | — | EP | disclosed |
| US-6693105-B1 | USING XANTHINYL DERIVATIVES TO REDUCE TREATMENT INDUCED TOXICITY; INHIBITING CELLULAR SIGNALING THROUGH SECOND MESSENGER PATHWAY; REDUCING CELLULAR LEVEL OF NONARACHI-DONATE PHOSPHATIDIC ACID AND DIACYLGLYCEROL | CELL THERAPEUTICS, INC. | 2004-02-17 | — | — | US | disclosed |
| US-6133274-A | TREATING DISEASE MEDIATED BY INTRACELLULAR SIGNALING THROUGH ONE OR TWO SPECIFIC INTRACELLULAR SIGNALING PATHWAYS; A XANTHINYL HAVING AT LEAST ONE NITROGEN SUBSTITUTED BY AN HYDROXYALKYL; ANTITUMOR,-CARCINOGENIC,-ARTHRITIC AGENTS | CELL THERAPEUTICS, INC. (US) | 2000-10-17 | — | — | US | disclosed |
| US-5780476-A | ADMINISTERING TO TREAT INFLAMMATORY DISEASE AND RHEUMATOID ARTHITIS | CELL THERAPEUTICS, INC. (US) | 1998-07-14 | — | — | US | disclosed |
| EP-0669825-A4 | HYDROXYL-CONTAINING COMPOUNDS. | CELL THERAPEUTICS INC (US) | 1996-04-03 | — | — | EP | disclosed |
| EP-0669825-A1 | HYDROXYL-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1995-09-06 | — | — | EP | disclosed |
| WO-1994011001-A1 | HYDROXYL-CONTAINING COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-05-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200291178-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | H1-2, H1-0, H1-3 | HDAC1 24/4885HDAC7 568/4885ALDH1A1 894/4885 |
| US-11529423-B2 | Biodegradable polyethylene glycol derivative having cyclic benzylidene acetal linker | AMDHD2, PGD, TREH | HDAC1 32/4885HDAC7 44/4885ALDH1A1 405/4885 |
| US-10808050-B2 | Antibody-drug conjugate having cyclic benzylidene acetal linker | H1-2, CD22, H1-0 | HDAC1 53/4885HDAC7 350/4885ALDH1A1 399/4885 |
| US-11041052-B2 | Biodegradable hydrogel having cyclic benzylidene acetal structure | H1-0, H1-2, H1-4 | HDAC1 20/4885HDAC7 183/4885ALDH1A1 99/4885 |
| US-20170290919-A1 | ANTIBODY-DRUG CONJUGATE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | H1-2, CD22, H1-0 | HDAC1 53/4885HDAC7 350/4885ALDH1A1 399/4885 |
| US-11530295-B2 | Hydrophilic polymer derivative having cyclic benzylidene acetal linker | H1-2, H1-0, H1-3 | HDAC1 24/4885HDAC7 568/4885ALDH1A1 894/4885 |
| US-20200289656-A1 | BIODEGRADABLE POLYETHYLENE GLYCOL DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | AMDHD2, PGD, TREH | HDAC1 32/4885HDAC7 44/4885ALDH1A1 405/4885 |
| US-20170107325-A1 | HYDROPHILIC POLYMER DERIVATIVE HAVING CYCLIC BENZYLIDENE ACETAL LINKER | H1-2, H1-0, H1-3 | HDAC1 25/4885HDAC7 550/4885ALDH1A1 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.