Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768386 | 0.88 | TLR7 (0.42) | ALDH1A1TLR7TLR8NUDT1 | |
| SCHEMBL6773457 | 0.83 | L3MBTL1 (0.42) | MEN1KMT2AALDH1A1POLBTLR7 | |
| SCHEMBL6897348 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TLR7TLR8NUDT1 | |
| SCHEMBL6773368 | 0.83 | TLR7 (0.43) | TLR7TLR8NUDT1 | |
| SCHEMBL6773193 | 0.82 | GNAI3 (0.39) | TLR7TLR8NUDT1 | |
| SCHEMBL6773840 | 0.81 | TLR7 (0.37) | ALDH1A1TLR7TLR8NUDT1 | |
| SCHEMBL6777299 | 0.81 | ALDH1A1 (0.43) | MEN1KMT2AALDH1A1LMNATLR7 | |
| SCHEMBL6288804 | 0.81 | TLR7 (0.41) | ALDH1A1RECQLTLR7HPGDTLR8 | |
| SCHEMBL6093363 | 0.81 | TLR7 (0.36) | TLR7TLR8NUDT1 | |
| SCHEMBL6279887 | 0.80 | TLR7 (0.41) | TLR7TLR8NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |