Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | BCR | P11274 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774104 | 0.94 | POLB (0.44) | GAAPOLBHTTTP53ABL1 | |
| SCHEMBL6773364 | 0.90 | RXFP1 (0.43) | GAAPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL6774657 | 0.89 | MAPT (0.49) | GAAPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL6768729 | 0.88 | TLR7 (0.47) | GAAPOLBHPGDKDM4EALDH1A1 | |
| SCHEMBL6771355 | 0.88 | POLB (0.47) | POLBHPGDKDM4EALDH1A1MAPT | |
| SCHEMBL6779087 | 0.87 | NOS3 (0.48) | GAAPOLBHPGDNAMPTKDM4E | |
| SCHEMBL6780394 | 0.86 | TRPV1 (0.47) | MAPT | |
| SCHEMBL6768482 | 0.85 | IDO1 (0.47) | POLBALDH1A1PKMTP53MAPT | |
| SCHEMBL6774081 | 0.85 | RAB9A (0.44) | POLBKDM4E | |
| SCHEMBL6772992 | 0.84 | HDAC3 (0.40) | GAANAMPTALDH1A1HTTCD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |