Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6772992 | 0.94 | HDAC3 (0.40) | RXFP1CD274EPHX2MAPTALDH1A1 | |
| SCHEMBL6773253 | 0.90 | GAA (0.41) | CD274MAPTALDH1A1GAAKDM4E | |
| SCHEMBL6780200 | 0.89 | ALDH1A1 (0.50) | RXFP1MAPTALDH1A1GAAPOLB | |
| SCHEMBL6780394 | 0.88 | TRPV1 (0.47) | EPHX2MAPTMCHR1TLR7HDAC3 | |
| SCHEMBL6774657 | 0.87 | MAPT (0.49) | MAPTALDH1A1GAAKDM4EGLA | |
| SCHEMBL6777601 | 0.87 | MEN1 (0.48) | EPHX2KDM4E | |
| SCHEMBL6768729 | 0.87 | TLR7 (0.47) | MAPTALDH1A1GAAKDM4EGLA | |
| SCHEMBL6771355 | 0.86 | POLB (0.47) | MAPTALDH1A1KDM4EHPGDPOLB | |
| SCHEMBL6773386 | 0.84 | TP53BP1 (0.49) | RXFP1MAPTALDH1A1GAAPOLB | |
| SCHEMBL6774104 | 0.84 | POLB (0.44) | GAAPOLBTP53NPC1TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |