Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 3/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | NOS2 | P35228 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773077 | 0.95 | MCHR1 (0.49) | MCHR1ADORA2AGAAGRM5NAMPT | |
| SCHEMBL6779087 | 0.89 | NOS3 (0.48) | GAAKDM4EALDH1A1PKMHPGD | |
| SCHEMBL6773842 | 0.86 | SMN1; SMN2 (0.50) | MCHR1ALDH1A1HPGDPOLBMAPT | |
| SCHEMBL6777400 | 0.85 | CCR3 (0.45) | MCHR1GAAKDM4EALDH1A1HPGD | |
| SCHEMBL6774657 | 0.85 | MAPT (0.49) | GAAKDM4EALDH1A1PKMHPGD | |
| SCHEMBL6780200 | 0.83 | ALDH1A1 (0.50) | GAAALDH1A1POLBNAMPTHDAC3 | |
| SCHEMBL6773853 | 0.83 | NOS3 (0.46) | GAAKDM4EALDH1A1PKMHPGD | |
| SCHEMBL6768482 | 0.83 | IDO1 (0.47) | ALDH1A1PKMPOLBHDAC3MAPT | |
| SCHEMBL6768596 | 0.82 | MCHR1 (0.47) | MCHR1ADORA2AGAANAMPTHDAC3 | |
| SCHEMBL6779684 | 0.81 | MCHR1 (0.50) | MCHR1GAAALDH1A1HPGDNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |