SCHEMBL677493

SCHEMBL677493

COc1c(C)cc(Cc2cc(C)cc(C)c2OC)cc1C

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 4/20 0.50
NR3C1 P04150 1/20 0.41
NR3C2 P08235 1/20 0.41
ACHE P22303 1/20 0.39
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 1/20 0.33
SLC22A1 O15245 1/20 0.33
CYP3A4 P08684 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
CYP2C19 P33261 1/20 0.33
BLM P54132 1/20 0.33
KMT2A Q03164 1/20 0.33
HSD17B10 Q99714 1/20 0.33
MAPT P10636 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTR2A P28223 1/20 0.32
HTR2C P28335 1/20 0.32
HTR2B P41595 1/20 0.32
SHBG P04278 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13550486 0.86 SHBG (0.47) DHFRNR3C1NR3C2ALDH1A1CYP2C19
SCHEMBL13304653 0.81 DHFR (0.51) DHFRNR3C1NR3C2ACHEALDH1A1
SCHEMBL678055 0.79 ACHE (0.44) DHFRNR3C1NR3C2ACHEALDH1A1
SCHEMBL129762 0.78 ACHE (0.57) NR3C1NR3C2ACHEALDH1A1MEN1
SCHEMBL13310100 0.78 DHFR (0.44) DHFRNR3C1NR3C2ACHEALDH1A1
SCHEMBL20362610 0.76 MAPT (0.47) NR3C1NR3C2ACHEALDH1A1KMT2A
SCHEMBL14076206 0.76 ACHE (0.41) DHFRNR3C1NR3C2ACHEALDH1A1
SCHEMBL21294089 0.73 SHBG (0.58) DHFRALDH1A1MAPTSHBG
SCHEMBL8427359 0.73 ACHE (0.39) DHFRNR3C1NR3C2ACHEALDH1A1
SCHEMBL20348768 0.73 CHRM2 (0.39) DHFRNR3C1NR3C2ACHEALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9080046-B2 Epoxybenzyl-terminated poly(arylene ether)s, method for preparation thereof, and curable compositions comprising same SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2015-07-14 US disclosed
US-8734693-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-05-27 US disclosed
US-20140058014-A1 EPOXYBENZYL-TERMINATED POLY(ARYLENE ETHER)S, METHOD FOR PREPARATION THEREOF, AND CURABLE COMPOSITIONS COMPRISING SAME SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-02-27 US disclosed
US-20130059127-A1 EPOXYBENZYL-TERMINATED POLY(ARYLENE ETHER)S, METHOD FOR PREPARATION THEREOF, AND CURABLE COMPOSITIONS COMPRISING SAME SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2013-03-07 US disclosed
US-20120277399-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2012-11-01 US disclosed
US-8075812-B2 Method of separating a poly(arylene ether) composition from a solvent, and poly(arylene ether) composition prepared thereby SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-13 US disclosed
US-8053077-B2 Composite-forming method, composites formed thereby, and printed circuit boards incorporating them SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-11-08 US disclosed
US-20100084170-A1 COMPOSITE-FORMING METHOD, COMPOSITES FORMED THEREBY, AND PRINTED CIRCUIT BOARDS INCORPORATING THEM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2010-04-08 US disclosed
US-7655278-B2 Composite-forming method, composites formed thereby, and printed circuit boards incorporating them SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-02-02 US disclosed
US-7582691-B2 Poly(arylene ether) compositions and articles SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-09-01 US disclosed
US-20080246173-A1 METHOD OF SEPARATING A POLY(ARYLENE ETHER) COMPOSITION FROM A SOLVENT, AND POLY(ARYLENE ETHER) COMPOSITION PREPARED THEREBY SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-10-09 US disclosed
US-20080178983-A1 COMPOSITE-FORMING METHOD, COMPOSITES FORMED THEREBY, AND PRINTED CIRCUIT BOARDS INCORPORATING THEM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-07-31 US disclosed
US-20080171817-A1 POLY(ARYLENE ETHER) COMPOSITIONS AND ARTICLES SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2008-07-17 US disclosed