SCHEMBL6775957

SCHEMBL6775957

CCc1ccc(C(F)c2c(Cl)nc(C#N)n2S(=O)(=O)N(C)C)cc1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1074601 0.79 TSHR (0.34) HPGD
SCHEMBL933331 0.74 TSHR (0.34) HPGD
SCHEMBL9519745 0.69 SMN1; SMN2 (0.33)
SCHEMBL8432137 0.68
SCHEMBL9519740 0.66 PTGS2 (0.39) HPGD
Cyazofamid SCHEMBL16180421 0.65 PTGS2 (0.38)
SCHEMBL9323957 0.64
SCHEMBL1074589 0.63 PTGS1 (0.41) HPGD
SCHEMBL9519533 0.62 HTT (0.31)
SCHEMBL5718754 0.62 SMN1; SMN2 (0.38) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6713500-B2 IMIDAZOLE DERIVATIVES; FOR CONTROLLING COCCIDIOSIS ISHIHARA SANGYO KAISHA LTD. (JP) 2004-03-30 US claimed
US-6713500-B2 IMIDAZOLE DERIVATIVES; FOR CONTROLLING COCCIDIOSIS ISHIHARA SANGYO KAISHA LTD. (JP) 2004-03-30 US disclosed
US-20030100586-A1 Agent for controlling animal diseases caused by parasites ISHIHARA SANGYO KAISHA LTD. (JP) 2003-05-29 US disclosed
EP-1211245-A1 AGENTS FOR CONTROLLING ANIMAL DISEASES CAUSED BY PARASITES ISHIHARA SANGYO KAISHA, LTD. (JP) 2002-06-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030100586-A1 Agent for controlling animal diseases caused by parasites CLIC1, CLIC4, H1-4 HPGD 4313/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.