Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 8/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778839 | 0.91 | MAPKAPK2 (0.43) | QPCTMAPKAPK2SMN1; SMN2MAPTGAA | |
| SCHEMBL6782830 | 0.89 | HPGD (0.54) | SMN1; SMN2MAPTMAPK1ALDH1A1LMNA | |
| SCHEMBL6776249 | 0.85 | QPCT (0.47) | QPCTMAPKAPK2MAOBSMN1; SMN2MAPT | |
| SCHEMBL6778794 | 0.85 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTALDH1A1KMT2AHPGD | |
| SCHEMBL6779782 | 0.84 | QPCT (0.46) | QPCTMAPKAPK2MAOBSMN1; SMN2MAPT | |
| SCHEMBL6779540 | 0.82 | MAPT (0.44) | MAPTALDH1A1KMT2AHPGD | |
| SCHEMBL6777534 | 0.81 | TLR7 (0.36) | MAPTALDH1A1LMNA | |
| SCHEMBL6775204 | 0.81 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1KMT2AMEN1 | |
| SCHEMBL6776505 | 0.81 | PKM (0.45) | MAPTALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL6779814 | 0.81 | FAAH (0.47) | MAPKAPK2MAPTALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |