Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.39 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6769850 | 0.87 | OPRM1 (0.38) | L3MBTL1OPRM1MAPTALDH1A1MGLL | |
| SCHEMBL6769518 | 0.85 | L3MBTL1 (0.49) | L3MBTL1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6771511 | 0.85 | L3MBTL1 (0.49) | L3MBTL1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6772503 | 0.85 | OPRM1 (0.40) | CSNK2A2CSNK2BCSNK2A1ABCG2CSNK2A3 | |
| SCHEMBL6168193 | 0.85 | ABCG2 (0.42) | CSNK2A2CSNK2BCSNK2A1ABCG2CSNK2A3 | |
| SCHEMBL6770960 | 0.81 | SRC (0.43) | L3MBTL1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6767198 | 0.80 | L3MBTL1 (0.44) | L3MBTL1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6770500 | 0.80 | OPRM1 (0.61) | OPRM1 | |
| SCHEMBL6771222 | 0.80 | OPRM1 (0.47) | L3MBTL1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6162980 | 0.76 | CCNA2 (0.40) | CSNK2A2CSNK2BCSNK2A1ABCG2CSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |