Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.36 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | BUB1 | O43683 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6168193 | 0.87 | ABCG2 (0.42) | OPRM1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6777334 | 0.85 | L3MBTL1 (0.47) | OPRM1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6771250 | 0.84 | OPRM1 (0.45) | OPRM1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6776388 | 0.84 | OPRM1 (0.38) | OPRM1SRCBUB1 | |
| SCHEMBL6770603 | 0.81 | CSNK2A2 (0.40) | OPRM1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6771234 | 0.81 | CSNK2A2 (0.35) | OPRM1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6771222 | 0.79 | OPRM1 (0.47) | OPRM1CSNK2A2CSNK2BCSNK2A1ABCG2 | |
| SCHEMBL6771178 | 0.79 | SRC (0.43) | OPRM1CSNK2BCSNK2A1SRCALDH1A1 | |
| SCHEMBL6766804 | 0.79 | OPRM1 (0.64) | OPRM1 | |
| SCHEMBL6770545 | 0.78 | ABCG2 (0.38) | CSNK2A2CSNK2BCSNK2A1ABCG2CSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6716856-B1 | CELL PROLIFERATIVE DISORDERS OR ALZHEIMER'S DISEASE; REDUCED TOXICITY; CDK/CYCLIN KINASE INHIBITORY ACTIVITY | PHARMACIA & TUBJOHN SPA (IT) | 2004-04-06 | — | — | US | disclosed |