Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778719 | 0.95 | KMT2A (0.48) | MAPTRAB9ANPC1LMNANFKB1 | |
| SCHEMBL6773506 | 0.87 | NPC1 (0.47) | MAPTRAB9ANPC1KMT2AHTT | |
| SCHEMBL6776784 | 0.86 | ALDH1A1 (0.48) | LMNAKMT2AHTTHSD17B10MEN1 | |
| SCHEMBL6773842 | 0.85 | SMN1; SMN2 (0.50) | MAPTRAB9ANPC1KMT2AHTT | |
| SCHEMBL6777400 | 0.85 | CCR3 (0.45) | MAPTRAB9ANPC1LMNAKMT2A | |
| SCHEMBL6777586 | 0.83 | PKM (0.47) | MAPTRAB9ANPC1LMNANFKB1 | |
| SCHEMBL6783335 | 0.82 | CCR3 (0.46) | MAPTRAB9ANPC1LMNAKMT2A | |
| SCHEMBL6772950 | 0.81 | FAAH (0.53) | MAPTRAB9ALMNAPKMHTT | |
| SCHEMBL6779213 | 0.81 | KMT2A (0.49) | MAPTRAB9ANPC1LMNANFKB1 | |
| SCHEMBL6778012 | 0.80 | CCR3 (0.45) | MAPTRAB9ALMNAKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720334-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; 1-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)-3-PHENYLUREA. | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |