Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778267 | 0.77 | METAP2 (0.40) | METAP2METAP1RAB9AALDH1A1IDO1 | |
| SCHEMBL8605901 | 0.75 | CHRNB4 (0.41) | METAP2METAP1RAB9AALDH1A1IDO1 | |
| SCHEMBL1356987 | 0.74 | METAP2 (0.45) | METAP2METAP1RAB9AALDH1A1IDO1 | |
| SCHEMBL28797072 | 0.73 | CHRNB4 (0.42) | METAP2METAP1ALDH1A1IDO1CHRNB4 | |
| SCHEMBL1356989 | 0.70 | METAP2 (0.49) | METAP2METAP1RAB9AALDH1A1IDO1 | |
| SCHEMBL61120 | 0.70 | IDO1 (0.44) | METAP2METAP1RAB9AALDH1A1IDO1 | |
| SCHEMBL247214 | 0.68 | ADH1A (0.37) | EPHX1 | |
| SCHEMBL8802609 | 0.68 | ADH1B (0.31) | — | |
| SCHEMBL29191681 | 0.68 | ALDH1A3 (0.52) | RAB9AALDH1A1NPC1 | |
| SCHEMBL8403428 | 0.68 | METAP2 (0.47) | METAP2METAP1RAB9AALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6770780-B1 | QUATERNIZATION OF T-BUTYL BROMOACETATE WITH TRI(N-BUTYL)PHOSPHINE TO FORM PHOSPHONIUM SALT; REACTING WITH BASE TO FORM PHOSPHORUS YLIDE; FORMING 2,4,6-TRIS(3', 5'-DI-T-BUTYL-4'-HYDROXYBENZYL)METHYL-STYRENE; HYDROLYSIS | JSR CORPORATION (JP) | 2004-08-03 | — | — | US | disclosed |
| EP-1231205-A1 | VINYLPHENYLPROPIONIC ACID DERIVATIVES, PROCESSES FOR PRODUCTION OF THE DERIVATIVES, POLYMERS THEREOF AND RADIOSENSITIVE RESIN COMPOSITIONS | JSR Corporation (JP) | 2002-08-14 | — | — | EP | disclosed |