Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778453 | 1.00 | TDP1 (0.47) | TDP1GAAUSP2RXFP1KDM4E | |
| SCHEMBL15196535 | 0.78 | USP2 (0.73) | TDP1GAAUSP2RXFP1KDM4E | |
| SCHEMBL22900275 | 0.71 | CCR1 (0.45) | GAAUSP2RXFP1KDM4EALDH1A1 | |
| SCHEMBL29009203 | 0.70 | MEN1 (0.43) | TDP1GAARXFP1KDM4EALDH1A1 | |
| SCHEMBL19732957 | 0.69 | GAA (0.67) | TDP1GAAUSP2RXFP1KDM4E | |
| SCHEMBL19732950 | 0.69 | GAA (0.67) | TDP1GAAUSP2RXFP1KDM4E | |
| SCHEMBL19732951 | 0.69 | GAA (0.67) | TDP1GAAUSP2RXFP1KDM4E | |
| SCHEMBL29009154 | 0.67 | GAA (0.42) | TDP1GAARXFP1KDM4EALDH1A1 | |
| SCHEMBL10153183 | 0.66 | GAA (0.56) | TDP1GAAUSP2RXFP1MAPT | |
| SCHEMBL14413503 | 0.66 | GAA (0.64) | TDP1GAAUSP2RXFP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | claimed |