Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677655 | 0.80 | MAPK1 (0.55) | ALDH1A1TDP1NPSR1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL20984256 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPK1L3MBTL1MEN1 | |
| Bromide SCHEMBL20984424 | 0.79 | ALDH1A1 (0.46) | ALDH1A1TDP1MAPK1L3MBTL1MEN1 | |
| SCHEMBL358770 | 0.79 | TDP1 (0.61) | ALDH1A1TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL29154936 | 0.78 | PDK1 (0.44) | ALDH1A1TDP1NPSR1MAPK1L3MBTL1 | |
| Nitric Acid SCHEMBL20984791 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TDP1MAPK1L3MBTL1MEN1 | |
| SCHEMBL20984593 | 0.76 | ALDH1A1 (0.47) | ALDH1A1TDP1MAPK1MEN1KMT2A | |
| SCHEMBL2949659 | 0.76 | TDP1 (0.54) | ALDH1A1TDP1NPSR1L3MBTL1KMT2A | |
| Sulfuric Acid SCHEMBL20984945 | 0.75 | F2 (0.46) | ALDH1A1TDP1MAPK1MEN1KMT2A | |
| Phosphoric Acid SCHEMBL20984988 | 0.75 | KMT2A (0.44) | ALDH1A1TDP1MAPK1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743788-B2 | ANTIINFLAMMATORY AGENTS; AUTOIMMUNE DISEASE; AUTOIMMUNE DISEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2004-06-01 | — | — | US | disclosed |
| US-20030092702-A1 | Novel carbamate and oxamide compounds | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030092702-A1 | Novel carbamate and oxamide compounds | IFNG, CXCR1, ARG1 | ALDH1A1 1014/4885TDP1 3340/4885NPSR1 2133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.