Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6774160 | 0.90 | HPGD (0.47) | GAAHPGDMEN1KMT2ATMIGD3 | |
| SCHEMBL6774520 | 0.88 | TP53 (0.37) | ALDH1A1MAPTTMIGD3ADORA2AADORA1 | |
| SCHEMBL6768483 | 0.86 | DRD3 (0.44) | ALDH1A1GAAMAPTMEN1KMT2A | |
| SCHEMBL5746744 | 0.85 | TLR7 (0.51) | ALDH1A1TRPV1GAAHPGDATM | |
| SCHEMBL6773389 | 0.85 | HPGD (0.43) | ALDH1A1HPGDMEN1KMT2AHSD17B10 | |
| SCHEMBL6777509 | 0.84 | FAAH (0.47) | ALDH1A1GAAHPGDMAPTMEN1 | |
| SCHEMBL6778367 | 0.83 | LMNA (0.44) | ALDH1A1GAAHPGDMAPTMEN1 | |
| SCHEMBL6098139 | 0.83 | DYRK1A (0.37) | ALDH1A1 | |
| SCHEMBL6775246 | 0.83 | HDAC1 (0.41) | ALDH1A1KMT2AADORA2A | |
| SCHEMBL6778477 | 0.82 | QPCT (0.44) | GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |