Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TMIGD3 | P0DMS9 | 3/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6773010 | 0.90 | ALDH1A1 (0.43) | HPGDGAATMIGD3ADORA2AADORA1 | |
| SCHEMBL6774520 | 0.86 | TP53 (0.37) | LMNATMIGD3ADORA2AADORA1L3MBTL1 | |
| SCHEMBL3863867 | 0.86 | TLR7 (0.49) | HPGDLMNAADORA2A | |
| SCHEMBL6778367 | 0.86 | LMNA (0.44) | HPGDGAALMNAKDM4ETMIGD3 | |
| SCHEMBL6775246 | 0.85 | HDAC1 (0.41) | ADORA2AKMT2AL3MBTL1HDAC1HDAC2 | |
| SCHEMBL6768483 | 0.84 | DRD3 (0.44) | GAALMNAKMT2ADRD2DRD3 | |
| SCHEMBL6777509 | 0.83 | FAAH (0.47) | HPGDGAALMNAKDM4EKMT2A | |
| SCHEMBL6098139 | 0.82 | DYRK1A (0.37) | KDM4E | |
| SCHEMBL6772471 | 0.81 | HPGD (0.46) | HPGDGAALMNAKDM4EKMT2A | |
| SCHEMBL6779152 | 0.81 | TLR7 (0.40) | HPGDLMNAKDM4ETMIGD3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |