Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ERN1 | O75460 | 9/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9242468 | 0.94 | KIF11 (0.39) | KIF11TDP1ERN1KDREPAS1 | |
| SCHEMBL3620779 | 0.88 | TDP1 (0.39) | KIF11TDP1ERN1KDRALDH1A1 | |
| SCHEMBL9342590 | 0.83 | KIF11 (0.44) | KIF11ERN1 | |
| SCHEMBL2966961 | 0.80 | ERN1 (0.40) | KIF11TDP1ERN1 | |
| SCHEMBL9340602 | 0.78 | KIF11 (0.39) | KIF11TDP1ERN1KDR | |
| SCHEMBL7272536 | 0.78 | TDP1 (0.42) | KIF11TDP1ERN1KDR | |
| SCHEMBL8672712 | 0.76 | TDP1 (0.48) | TDP1ERN1ALDH1A1 | |
| SCHEMBL9628313 | 0.76 | KIF11 (0.36) | KIF11TDP1KDRALDH1A1 | |
| SCHEMBL8462010 | 0.76 | HTR3E (0.41) | TDP1KDRALDH1A1 | |
| SCHEMBL604322 | 0.76 | TDP1 (0.43) | TDP1ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148682-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
| EP-2376441-A2 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | Dow AgroSciences LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| EP-2376435-A2 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | Dow AgroSciences LLC (US) | 2011-10-19 | — | — | EP | disclosed |
| WO-2010083307-A2 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2010-07-22 | — | — | WO | disclosed |
| WO-2010083310-A2 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2010-07-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | KIF11 2403/4885TDP1 3561/4885ERN1 3396/4885 |
| US-20120148682-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | KIF11 2274/4885TDP1 2868/4885ERN1 3190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.