Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 1.00 |
| ▸ | POLB | P06746 | 3/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 1.00 |
| ▸ | APEX1 | P27695 | 1/20 | 1.00 |
| ▸ | FPR1 | P21462 | 3/20 | 0.80 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779640 | 0.86 | ALDH1A1 (0.76) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6780486 | 0.86 | ALDH1A1 (0.75) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6779502 | 0.81 | MEN1 (0.82) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6785309 | 0.77 | MEN1 (0.79) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6781053 | 0.77 | MEN1 (0.79) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6779616 | 0.76 | MEN1 (0.77) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6780434 | 0.76 | RXFP1 (0.78) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6781607 | 0.76 | MEN1 (1.00) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6780190 | 0.75 | ALOX15 (0.63) | ALDH1A1KDM4EPOLBTDP1APEX1 | |
| SCHEMBL6785761 | 0.74 | MEN1 (0.71) | ALDH1A1KDM4EPOLBTDP1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | claimed |
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | THE BURNHAM INSTITUTE (US) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118135-A1 | METHODS AND COMPOUNDS FOR REGULATING APOPTOSIS | BCL2, BAX, BAD | ALDH1A1 3724/4885KDM4E 3373/4885POLB 1539/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.