Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.51 |
| ▸ | DRD4 | P21917 | 11/20 | 0.49 |
| ▸ | DRD2 | P14416 | 9/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6768483 | 0.87 | DRD3 (0.44) | DRD2NPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL6769799 | 0.87 | MCHR1 (0.50) | MCHR1NAMPTGAADRD3 | |
| SCHEMBL6773548 | 0.86 | HDAC3 (0.49) | DRD4DRD2TP53MEN1KMT2A | |
| SCHEMBL6779213 | 0.86 | KMT2A (0.49) | MCHR1NPC1HTTRAB9AHSD17B10 | |
| SCHEMBL14111995 | 0.86 | DRD4 (0.52) | MCHR1DRD4DRD2NPC1TP53 | |
| SCHEMBL6773542 | 0.85 | TP53BP1 (0.48) | DRD2NAMPTALDH1A1DRD3 | |
| SCHEMBL6779684 | 0.82 | MCHR1 (0.50) | MCHR1DRD4DRD2NPC1TP53 | |
| SCHEMBL6774052 | 0.82 | POLB (0.43) | DRD4DRD2NPC1TP53RAB9A | |
| SCHEMBL6773439 | 0.81 | TRPV1 (0.44) | MCHR1NPC1RAB9A | |
| SCHEMBL6891296 | 0.80 | TP53 (0.50) | NPC1TP53HTTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6720333-B2 | IMMUNE RESPONSE MODIFIERS; CYTOKINE BIOSYNTHESIS; VIRAL AND NEOPLASTIC DISEASES; N-(4-(4-AMINO-6,7-DIMETHYL-1H-IMIDAZO (4,5-C)PYRIDIN-1-YL)BUTYL)BENZAMIDE | 3M INNOVATIVE PROPERTIES COMPANY | 2004-04-13 | — | — | US | claimed |