Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 3/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | GLA | P06280 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 2/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | APEX1 | P27695 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6779502 | 0.82 | MEN1 (0.82) | RXFP1POLBALDH1A1GAATSHR | |
| SCHEMBL6779616 | 0.82 | MEN1 (0.77) | RXFP1POLBALDH1A1GAATSHR | |
| SCHEMBL1520527 | 0.80 | ALDH1A1 (1.00) | RXFP1POLBALDH1A1GLAGAA | |
| SCHEMBL6786235 | 0.79 | ALDH1A1 (0.78) | RXFP1POLBALDH1A1GAATSHR | |
| SCHEMBL6781053 | 0.78 | MEN1 (0.79) | RXFP1POLBALDH1A1GAATSHR | |
| SCHEMBL6785309 | 0.78 | MEN1 (0.79) | POLBALDH1A1GAATSHRMEN1 | |
| SCHEMBL6781607 | 0.77 | MEN1 (1.00) | RXFP1POLBALDH1A1GAATSHR | |
| SCHEMBL6779753 | 0.76 | ALDH1A1 (1.00) | RXFP1POLBALDH1A1GLAGAA | |
| SCHEMBL6785134 | 0.76 | MEN1 (0.65) | POLBALDH1A1GAATSHRMEN1 | |
| SCHEMBL6780190 | 0.76 | ALOX15 (0.63) | RXFP1POLBALDH1A1GAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | claimed |