Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 2/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6781053 | 0.83 | MEN1 (0.79) | ALDH1A1KDM4EHPGDNPSR1POLB | |
| SCHEMBL6779502 | 0.79 | MEN1 (0.82) | ALDH1A1KDM4EHPGDNPSR1POLB | |
| SCHEMBL6780434 | 0.79 | RXFP1 (0.78) | ALDH1A1KDM4EHPGDNPSR1POLB | |
| SCHEMBL19420158 | 0.77 | KDM4E (0.68) | ALDH1A1KDM4EHPGDNPSR1RXFP1 | |
| SCHEMBL6785309 | 0.75 | MEN1 (0.79) | ALDH1A1KDM4EHPGDPOLBMEN1 | |
| SCHEMBL6781607 | 0.74 | MEN1 (1.00) | ALDH1A1KDM4EHPGDPOLBRXFP1 | |
| SCHEMBL6779616 | 0.74 | MEN1 (0.77) | ALDH1A1KDM4EHPGDPOLBRXFP1 | |
| SCHEMBL6779753 | 0.73 | ALDH1A1 (1.00) | ALDH1A1KDM4ENPSR1POLBRXFP1 | |
| SCHEMBL6780190 | 0.73 | ALOX15 (0.63) | ALDH1A1KDM4EHPGDNPSR1POLB | |
| SCHEMBL6785761 | 0.73 | MEN1 (0.71) | ALDH1A1KDM4EHPGDPOLBRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727275-B2 | ANTIINFLAMMATORY, ANTIALLERGEN, AND ANTIASTHMATIC AGENTS | UCB, S.A./N.V. (BE) | 2004-04-27 | — | — | US | claimed |