Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6780880 | 0.80 | NPC1 (0.58) | L3MBTL1KDM4EMAPTHSD11B1ALDH1A1 | |
| SCHEMBL6778832 | 0.80 | NPC1 (0.56) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL6780660 | 0.80 | KDM4E (0.49) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL6777807 | 0.74 | NOTUM (0.48) | L3MBTL1KDM4ES1PR1ALDH1A1FLT1 | |
| SCHEMBL6458875 | 0.72 | HSD17B10 (0.56) | L3MBTL1KDM4EMAPTHSD11B1S1PR1 | |
| SCHEMBL29975873 | 0.72 | MAPT (0.46) | L3MBTL1KDM4EMAPTHSD11B1GPBAR1 | |
| SCHEMBL6779584 | 0.72 | KDM4E (0.58) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL6776559 | 0.71 | NPC1 (0.54) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL27660142 | 0.70 | HSD11B1 (0.62) | L3MBTL1KDM4EMAPTHSD11B1S1PR1 | |
| SCHEMBL12666659 | 0.68 | L3MBTL1 (0.52) | L3MBTL1KDM4EMAPTHSD11B1S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521610-B2 | For controlling harmful insects, acarina and nematodes | HOECHST SCHERING AGREVO GMBH (DE) | 2003-02-18 | — | — | US | claimed |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | TIEBES JORG (DE) | 2002-01-31 | — | — | US | claimed |
| US-6239160-B1 | 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-29 | — | — | US | claimed |
| US-6699853-B2 | PROTECTING USEFUL PLANTS AGAINST THE UNDESIRABLE ACTION OF HARMFUL INSECTS, ACARIDS AND NEMATODES, | HOECHST SCHERING AGREVO GMBH (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | HARMSEN SVEN (DE) | 2003-08-28 | — | — | US | disclosed |
| US-6521610-B2 | For controlling harmful insects, acarina and nematodes | HOECHST SCHERING AGREVO GMBH (DE) | 2003-02-18 | — | — | US | disclosed |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | TIEBES JORG (DE) | 2002-01-31 | — | — | US | disclosed |
| US-6239160-B1 | 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-29 | — | — | US | disclosed |
| EP-0991648-A1 | 4-HALOALKYL-3- HETEROCYCLYLPYRIDINES AND 4-HALOALKYL -5-HETEROCYCLYLPYRIDINES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | Hoechst Schering AgrEvo GmbH (DE) | 2000-04-12 | — | — | EP | disclosed |
| WO-1998057969-A1 | 4-HALOALKYL-3- HETEROCYCLYLPYRIDINES AND 4-HALOALKYL -5-HETEROCYCLYLPYRIDINES, METHOD FOR THE PRODUCTION THEREOF, AGENTS CONTAINING THE SAME AND THEIR USE AS PESTICIDES | HOECHST SCHERING AGREVO GMBH (DE) | 1998-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HCK, HPD | L3MBTL1 3042/4885KDM4E 297/4885MAPT 4017/4885 |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HAX1, HDHD5 | L3MBTL1 1476/4885KDM4E 366/4885MAPT 4656/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.