Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | P4HB | P07237 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6785569 | 0.99 | MAPK1 (0.48) | MAPK1PKMSMN1; SMN2L3MBTL1LMNA | |
| SCHEMBL6783586 | 0.92 | MMP1 (0.50) | LMNAKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL6784583 | 0.92 | FAAH (0.46) | SMN1; SMN2KDM4EFAAHKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6779450 | 0.91 | FAAH (0.45) | SMN1; SMN2KDM4EFAAHKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6784819 | 0.91 | MMP1 (0.49) | LMNAKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL6780311 | 0.90 | MMP1 (0.48) | LMNAKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL6783968 | 0.89 | OPRL1 (0.44) | MAPK1KDM4EFAAHALDH1A1POLB | |
| SCHEMBL6783405 | 0.89 | SIGMAR1 (0.54) | LMNAKMT2AMEN1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL6783603 | 0.89 | MMP1 (0.48) | LMNAKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL6784165 | 0.89 | FAAH (0.47) | SMN1; SMN2KDM4EFAAHKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6710060-B2 | 4-hydroxypiperidine derivatives having antiarrhythmic activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-23 | — | — | US | disclosed |
| US-6642257-B2 | Fewer side-effects than do the conventional analgesics; 4-hydroxypiperidine derivatives | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2003-11-04 | — | — | US | disclosed |
| US-20020188006-A1 | 4-hydroxypiperidine derivatives having antiarrhythmic activity | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-12-12 | — | — | US | disclosed |
| US-20020049229-A1 | Agents for treating neuropathic pain | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-25 | — | — | US | disclosed |
| EP-1182193-A1 | REMEDIES FOR NEUROPATHIC PAIN | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-27 | — | — | EP | disclosed |
| EP-1182192-A1 | 4-HYDROXYPIPERIDINE DERIVATIVES HAVING ANTIARRHYTHMIC EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2002-02-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020049229-A1 | Agents for treating neuropathic pain | OPRM1, OPRK1, OPRL1 | MAPK1 1574/4885PKM 2897/4885SMN1; SMN2 379/4885 |
| US-20020188006-A1 | 4-hydroxypiperidine derivatives having antiarrhythmic activity | SCN5A, RYR2, SCN1B | MAPK1 721/4885PKM 928/4885SMN1; SMN2 524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.