Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 9/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.45 |
| ▸ | GABRP | O00591 | 1/20 | 0.43 |
| ▸ | GABRD | O14764 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.43 |
| ▸ | GABRE | P78334 | 1/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | BRD2 | P25440 | 1/20 | 0.38 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11002761 | 1.00 | CCKBR (0.45) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL6782014 | 0.83 | GABRA1 (0.76) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL27473419 | 0.82 | OPRK1 (0.54) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Ro-052921 SCHEMBL6779461 | 0.79 | GABRA1 (0.65) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL6782579 | 0.77 | GABRA1 (0.42) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL27473017 | 0.76 | LMNA (0.58) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL7211800 | 0.72 | NPSR1 (0.36) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL6629194 | 0.70 | CCKBR (0.57) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL28120473 | 0.70 | CCKBR (0.50) | CCKBRGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL27528226 | 0.68 | CCKBR (0.51) | CCKBRGABRA1GABRG2GABRB3GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6683075-B1 | FUSED NITROGENHETEROCYCLIC AMIDES; ALZHEIMER'S DISEASE | ATHENA NEUROSCIENCES, INC. | 2004-01-27 | — | — | US | disclosed |