Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.73 |
| ▸ | ERN1 | O75460 | 1/20 | 0.63 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 6/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5595086 | 1.00 | MAPT (0.73) | MAPTERN1GPR35MAOBKMT2A | |
| SCHEMBL5595081 | 1.00 | MAPT (0.73) | MAPTERN1GPR35MAOBKMT2A | |
| O-Coumaric Acid SCHEMBL6824128 | 0.93 | MAPT (0.68) | MAPTERN1GPR35MAOBKMT2A | |
| O-Coumaric Acid SCHEMBL6824137 | 0.93 | MAPT (0.68) | MAPTERN1GPR35MAOBKMT2A | |
| SCHEMBL6823892 | 0.89 | MAPT (0.59) | MAPTERN1GPR35MAOBKMT2A | |
| SCHEMBL5594855 | 0.86 | ERN1 (0.61) | MAPTERN1GPR35MAOBKMT2A | |
| SCHEMBL27516968 | 0.86 | ERN1 (0.61) | MAPTERN1GPR35MAOBKMT2A | |
| SCHEMBL10673342 | 0.85 | MAPT (1.00) | MAPTMAOBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL42323 | 0.85 | MAPT (1.00) | MAPTMAOBKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL820084 | 0.85 | MAPT (1.00) | MAPTMAOBKMT2AMEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737431-B2 | SUCH AS N-(3-(2-METHYLBENZOXAZOL-7-YL)PROPYL)PROPANAMIDE; CIRCADIAN RHYTHM RELATED DISORDERS | BRISTOL-MYERS SQUIBB COMPANY | 2004-05-18 | — | — | US | disclosed |
| US-20030216456-A1 | Benzoxazole derivatives as novel melatonergic agents | BRISTOL-MYERS SQUIBB COMPANY | 2003-11-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216456-A1 | Benzoxazole derivatives as novel melatonergic agents | MTNR1A, MTNR1B, MC1R | MAPT 3401/4885ERN1 4077/4885GPR35 53/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.