SCHEMBL67875

SCHEMBL67875

Oc1ccc(OF)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
TUBB1 Q9H4B7 1/20 0.31
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5053806 0.78 LMNA (0.43) KDM4EESR1ESR2AR
SCHEMBL714254 0.78 MAOB (0.46) KDM4ETUBB1
SCHEMBL29987655 0.78 PIM1 (0.41) KDM4EESR1ESR2AR
SCHEMBL1512796 0.78 PIM1 (0.41) KDM4EESR1ESR2AR
SCHEMBL28038952 0.75 ALDH1A1 (0.46) KDM4ETUBB1ESR1
SCHEMBL423475 0.75 ALDH1A1 (0.46) KDM4ETUBB1ESR1
SCHEMBL22279635 0.73 KCNH2 (0.37) TUBB1AR
SCHEMBL22208469 0.73 HSD17B1 (0.38) AR
SCHEMBL25797921 0.73 L3MBTL1 (0.39) ESR1
SCHEMBL25797857 0.73 L3MBTL1 (0.39) ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 KDM4E 717/4885TUBB1 2592/4885ESR1 1265/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.