Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.90 |
| ▸ | MEN1 | O00255 | 4/20 | 0.90 |
| ▸ | KCNK3 | O14649 | 6/20 | 0.81 |
| ▸ | KCNK9 | Q9NPC2 | 4/20 | 0.81 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.78 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.77 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 2/20 | 0.69 |
| ▸ | HPGD | P15428 | 1/20 | 0.69 |
| ▸ | TP53 | P04637 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2106175 | 0.98 | KMT2A (0.87) | KMT2AMEN1KCNK3KCNK9HPSE | |
| SCHEMBL9249052 | 0.96 | HPSE (0.84) | KMT2AMEN1KCNK3KCNK9HPSE | |
| SCHEMBL30686768 | 0.92 | MEN1 (0.83) | KMT2AMEN1KCNK3KCNK9HPSE | |
| SCHEMBL13381198 | 0.92 | L3MBTL1 (0.82) | KMT2AMEN1KCNK3KCNK9HPSE | |
| SCHEMBL14075235 | 0.92 | PARP1 (0.78) | KMT2AMEN1KCNK3KCNK9HPSE | |
| SCHEMBL2298254 | 0.90 | KCNK3 (1.00) | KMT2AMEN1KCNK3KCNK9SIRT1 | |
| SCHEMBL11474161 | 0.89 | KMT2A (0.79) | KMT2AMEN1KCNK3KCNK9HPSE | |
| SCHEMBL23070423 | 0.88 | KMT2A (0.80) | KMT2AMEN1KCNK3KCNK9HPSE | |
| SCHEMBL1814173 | 0.88 | KCNK3 (0.82) | KMT2AMEN1KCNK3KCNK9HPSE | |
| SCHEMBL11083807 | 0.88 | KCNK3 (0.82) | KMT2AMEN1KCNK3KCNK9HPSE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2023-12-28 | — | — | US | disclosed |
| US-20230373947-A1 | AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE | MITSUI CHEMICALS, INC. (JP) | 2023-11-23 | — | — | US | disclosed |
| US-11760742-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2023-09-19 | — | — | US | disclosed |
| US-20230165833-A1 | Selective Butyrylcholinesterase Inhibitor or Pharmaceutically Acceptable Salt Thereof, Preparation Method and Use Thereof | CHINA PHARMACEUTICAL UNIVERSITY (CN) | 2023-06-01 | — | — | US | disclosed |
| WO-2022109469-A1 | COMPOUNDS AND METHODS TO TARGET GLUCOSE-STIMULATED PHOSPHOHISTIDINE SIGNALING AND ESOPHAGEAL CANCER GROWTH | HEALTH RESEARCH, INC. (US) | 2022-05-27 | — | — | WO | disclosed |
| WO-2022087630-A1 | INHIBITORS OF AMINO ACID TRANSPORT | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (US) | 2022-04-28 | — | — | WO | disclosed |
| US-20210230135-A1 | AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE | MITSUI CHEMICALS, INC. (JP) | 2021-07-29 | — | — | US | disclosed |
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | SANOFI (FR) | 2021-06-10 | — | — | US | disclosed |
| US-10995081-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | MITSUI CHEMICALS, INC. (JP) | 2021-05-04 | — | — | US | disclosed |
| WO-2021042410-A1 | SELECTIVE BUTYRYLCHOLINESTERASE INHIBITOR OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 中国药科大学 | 2021-03-11 | — | — | WO | disclosed |
| CN-1051548-C | Heterobicyclic derivatives, pharmaceutical compositions containing them, process for preparing them and their use | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-04-19 | — | — | CN | disclosed |
| CN-1250776-A | Heterodicyclic compound derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-04-19 | — | — | CN | disclosed |
| EP-0920867-A1 | Pyrido[2,3-a]pyrazine derivatives as PDE-IV and TNF inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-06-09 | — | — | EP | disclosed |
| CN-1157617-A | Heterobicyclic derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-08-20 | — | — | CN | disclosed |
| EP-0770079-A1 | HETEROBICYCLIC DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001825-A1 | HETEROBICYCLIC DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-01-25 | — | — | WO | disclosed |
| EP-0246570-B1 | ZINC AND/OR LEAD SALTS OF CARBOXYLIC ACIDS AND THEIR USE AS ANTICORROSIVES | BASF Lacke + Farben AG (DE) | 1989-09-13 | — | — | EP | disclosed |
| US-4830775-A | FOR AQUEOUS COATING SYSTEMS | BASF Lacke ± Farben Aktiengesellschaft (DE) | 1989-05-16 | — | — | US | disclosed |
| EP-0246570-A1 | Zinc and/or lead salts of carboxylic acids and their use as anticorrosives | BASF Lacke + Farben AG (DE) | 1987-11-25 | — | — | EP | disclosed |
| US-4439444-A | HISTAMINE RECEPTOR ANTAGONISTS | SANOFI (FR) | 1984-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373947-A1 | AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE | DDT, CYP4B1, CYP2E1 | KMT2A 565/4885MEN1 2759/4885KCNK3 3042/4885 |
| US-20230165833-A1 | Selective Butyrylcholinesterase Inhibitor or Pharmaceutically Acceptable Salt Thereof, Preparation Method and Use Thereof | BCHE, ACHE, BACE1 | KMT2A 2073/4885MEN1 2484/4885KCNK3 1980/4885 |
| US-20210230135-A1 | AMIDE DERIVATIVES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS INSECTICIDE | DDT, CYP4B1, CYP2E1 | KMT2A 565/4885MEN1 2759/4885KCNK3 3042/4885 |
| US-20230416199-A1 | INHIBITORS OF AMINO ACID TRANSPORT | SLC1A5, SLC7A1, SLC7A5 | KMT2A 2152/4885MEN1 2203/4885KCNK3 4351/4885 |
| US-20210170033-A1 | NOVEL CONJUGATES OF A PHARMACEUTICAL AGENT AND A MOIETY CAPABLE OF BINDING TO A GLUCOSE SENSING PROTEIN | GPR119, SLC2A8, SLC2A4 | KMT2A 4555/4885MEN1 1749/4885KCNK3 4073/4885 |
| US-11760742-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | DDT, CYP4B1, CYP2E1 | KMT2A 565/4885MEN1 2759/4885KCNK3 3042/4885 |
| US-10995081-B2 | Amide derivatives, process for preparation thereof and use thereof as insecticide | DDT, CYP4B1, CYP2E1 | KMT2A 565/4885MEN1 2759/4885KCNK3 3042/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.