Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | SMO | Q99835 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.48 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MTTP | P55157 | 7/20 | 0.46 |
| ▸ | APOB | P04114 | 5/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TEK | Q02763 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792281 | 0.89 | SMO (0.62) | ALDH1A1SMOKDRTRPV1LMNA | |
| SCHEMBL7086824 | 0.89 | LMNA (0.48) | ALDH1A1SMOKDRTRPV1CHRNB2 | |
| SCHEMBL7086840 | 0.87 | ALDH1A1 (0.44) | ALDH1A1KDRTRPV1CHRNB2CHRNB4 | |
| SCHEMBL6795383 | 0.82 | LMNA (0.52) | ALDH1A1SMOTRPV1LMNAHTT | |
| SCHEMBL6800058 | 0.82 | SMO (0.49) | ALDH1A1SMOTRPV1LMNAHTT | |
| SCHEMBL6787209 | 0.80 | PTGS1 (0.51) | ALDH1A1SMOLMNAHTTMTTP | |
| SCHEMBL6805191 | 0.80 | SMO (0.51) | ALDH1A1SMOLMNAMTTPAPOB | |
| SCHEMBL7086836 | 0.80 | TYK2 (0.47) | ALDH1A1TRPV1CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL6793985 | 0.79 | SMO (0.60) | ALDH1A1SMOKDRTRPV1LMNA | |
| SCHEMBL6794206 | 0.79 | LMNA (0.60) | SMOLMNAHTTMTTPAPOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | ALDH1A1 1427/4885SMO 2094/4885KDR 3180/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.