Biphenyl

Biphenyl

SCHEMBL6791933

CCCCNC.CCCCNC.CCCCNC.Fc1c(F)c(F)c(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1c(F)c(F)c(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1c(F)c(F)c(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.Fc1c(F)c(F)c(-c2c(F)c(F)c(F)c(F)c2F)c(F)c1F.OB(O)O.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC3 O15379 2/20 0.41
HDAC1 Q13547 2/20 0.41
HDAC2 Q92769 2/20 0.41
HDAC8 Q9BY41 1/20 0.41
NCOR2 Q9Y618 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SIGMAR1 Q99720 1/20 0.37
HTR1B P28222 1/20 0.37
PCSK9 Q8NBP7 1/20 0.37
HTR2A P28223 1/20 0.37
HRH1 P35367 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.35
TSHR P16473 1/20 0.35
HTT P42858 1/20 0.35
POLB P06746 1/20 0.34
ACP1 P24666 1/20 0.34
DRD2 P14416 1/20 0.34
DRD4 P21917 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL7608054 0.87 DRD2 (0.48) HDAC3HDAC1HDAC2HDAC8NCOR2
Biphenyl SCHEMBL6470283 0.82 EPHX2 (0.39) SIGMAR1
Biphenyl SCHEMBL5716291 0.82 L3MBTL1 (0.52) HDAC3HDAC1HDAC2HDAC8NCOR2
SCHEMBL5716334 0.80 EPHX1 (0.50) HDAC3HDAC1HDAC2L3MBTL1MEN1
Biphenyl SCHEMBL5716460 0.75 EPHX1 (0.62) L3MBTL1MEN1KMT2ASIGMAR1HTR1B
SCHEMBL7612327 0.73 TAAR1 (0.43) HDAC3HDAC1HDAC2HDAC8L3MBTL1
Phenol SCHEMBL27585794 0.71 L3MBTL1 (0.48) HDAC3HDAC1HDAC2HDAC8NCOR2
Biphenyl SCHEMBL6798167 0.71 EPHX2 (0.39) MEN1KMT2ASIGMAR1SMN1; SMN2DRD2
Boric Acid SCHEMBL23928392 0.70 MGLL (0.41) PCSK9HTT
Boric Acid SCHEMBL6065759 0.70 MGLL (0.41) PCSK9HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6822057-B2 OLEFIN POLYMERIZATION CATALYST SYSTEM IS A REACTION PRODUCT OF A METALLOCENES AND A COCATALYST CONTAINING FLUOROARYL SUBSTITUTED SECONDARY AMINE OR PHSOPHINE COMPOUND AND AN ANION CONTAINING GROUP 13 ELEMENT WHICH IS NONCOORDINATIG EXXON MOBIL CHEMICAL PATENTS INC. 2004-11-23 US disclosed
US-6489480-B2 COORDINATION POLYMERIZATION CATALYST FOR ALPHA-OLEFINS EXXONMOBIL CHEMICAL PATENTS INC. 2002-12-03 US disclosed
US-20020115806-A1 Olefin polymerization catalysts derived from Group-15 cationic compounds and processes using them EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-22 US disclosed
US-20020111265-A1 GROUP-15 CATIONIC COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. 2002-08-15 US disclosed