Biphenyl

Biphenyl

SCHEMBL5716291

CCCCNC.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.52

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.52
MEN1 O00255 1/20 0.52
KMT2A Q03164 1/20 0.52
HTR2A P28223 2/20 0.50
HRH1 P35367 2/20 0.50
SIGMAR1 Q99720 2/20 0.50
HTR1B P28222 2/20 0.50
HDAC3 O15379 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
NCOR2 Q9Y618 1/20 0.50
EPHX1 P07099 1/20 0.48
ATM Q13315 1/20 0.46
TAAR1 Q96RJ0 1/20 0.46
ACP1 P24666 1/20 0.44
TLR8 Q9NR97 1/20 0.42
TSHR P16473 2/20 0.42
HTT P42858 1/20 0.42
HTR1D P28221 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL5716460 0.91 EPHX1 (0.62) L3MBTL1MEN1KMT2AHTR2AHRH1
Biphenyl SCHEMBL7742046 0.84 SIGMAR1 (0.59) SIGMAR1HDAC3HDAC1HDAC2HDAC8
Phenol SCHEMBL27585794 0.83 L3MBTL1 (0.48) L3MBTL1MEN1KMT2AHTR2AHRH1
SCHEMBL7612327 0.82 TAAR1 (0.43) L3MBTL1MEN1KMT2AHTR2AHRH1
Biphenyl SCHEMBL6791933 0.82 HDAC3 (0.41) L3MBTL1MEN1KMT2AHTR2AHRH1
Biphenyl SCHEMBL5716264 0.80 DRD2 (0.58) SIGMAR1HDAC3HDAC1HDAC2HDAC8
Biphenyl SCHEMBL15347228 0.80 ALDH1A1 (0.56) L3MBTL1MEN1KMT2ASIGMAR1HDAC3
Biphenyl SCHEMBL5868585 0.80 ALDH1A1 (0.56) L3MBTL1HDAC3HDAC1HDAC2HDAC8
Styrene SCHEMBL10628549 0.78 TSHR (0.52) L3MBTL1MEN1KMT2AHTR2AHRH1
Biphenyl SCHEMBL5716330 0.78 ALDH1A1 (0.53) L3MBTL1HTR2AHRH1SIGMAR1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1661900-A1 Olefin polymerization cocatalysts derived from group-15 cationic compounds and processes using them ExxonMobil Chemical Patents Inc. (US) 2006-05-31 EP disclosed
EP-1252166-B1 OLEFIN POLYMERIZATION COCATALYSTS DERIVED FROM GROUP-15 CATIONIC COMPOUNDS AND PROCESSES USING THEM EXXONMOBIL CHEM PATENTS INC (US) 2005-11-09 EP disclosed