Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | MMP9 | P14780 | 4/20 | 0.39 |
| ▸ | MMP14 | P50281 | 4/20 | 0.39 |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP3 | P08254 | 3/20 | 0.39 |
| ▸ | MMP8 | P22894 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749955 | 0.90 | MMP1 (0.46) | MMP13MMP2MMP9MMP14MMP1 | |
| SCHEMBL6785881 | 0.87 | MMP13 (0.49) | MMP13MMP2MMP9MMP14MMP1 | |
| SCHEMBL6785681 | 0.82 | OPRM1 (0.40) | KMT2ASMN1; SMN2LMNAL3MBTL1OPRM1 | |
| SCHEMBL6789714 | 0.78 | MMP1 (0.50) | MMP13MMP2MMP9MMP14MMP1 | |
| SCHEMBL6791943 | 0.76 | MMP1 (0.59) | MMP13MMP2MMP9MMP14MMP1 | |
| SCHEMBL6785767 | 0.75 | KCNA3 (0.49) | MMP13MMP2MMP9MMP1MMP3 | |
| SCHEMBL6795694 | 0.74 | MMP1 (0.59) | MMP13MMP2MMP9MMP14MMP1 | |
| SCHEMBL6785500 | 0.70 | OPRM1 (0.50) | SMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL6792766 | 0.69 | MMP1 (0.65) | MMP13MMP2MMP9MMP14MMP1 | |
| SCHEMBL5919389 | 0.69 | MMP13 (0.79) | MMP13MMP2MMP9MMP14MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097487-A1 | Aromatic sulfonyl alpha-cycloamino hydroxamic acid compounds | G.D. SEARLE & CO. | 2004-05-20 | — | — | US | disclosed |
| US-6638952-B1 | Matrix metalloprotease inhibitors | PHARMACIA CORPORATION | 2003-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097487-A1 | Aromatic sulfonyl alpha-cycloamino hydroxamic acid compounds | MMP1, MMP2, MMP10 | MMP13 10/4885MMP2 2/4885MMP9 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.