Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | BPTF | Q12830 | 2/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.33 |
| ▸ | TUBB | P07437 | 7/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6787706 | 0.86 | TUBB4A (0.47) | KDM4EALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL6785181 | 0.82 | ATM (0.43) | NPC1RAB9AKDM4EALDH1A1PKM | |
| SCHEMBL6785055 | 0.80 | TUBB4A (0.41) | RAB9AKDM4EALDH1A1PRMT5TUBB4A | |
| SCHEMBL6785571 | 0.76 | PDPK1 (0.37) | ALDH1A1PRMT5TUBB4ATUBBTUBA3C | |
| SCHEMBL6785261 | 0.76 | TUBB4A (0.38) | ALDH1A1PRMT5TUBB4ATUBBTUBA3C | |
| SCHEMBL6786202 | 0.74 | TUBB4A (0.36) | KDM4EALDH1A1TP53GAAHSD17B10 | |
| SCHEMBL6785029 | 0.74 | ELANE (0.43) | KDM4EALDH1A1TP53GAAPKM | |
| SCHEMBL6787760 | 0.70 | MAPT (0.43) | KDRKDM4EALDH1A1HSD17B10BPTF | |
| SCHEMBL6784727 | 0.67 | KDR (0.43) | KITKDRFLT3BPTFPRMT5 | |
| Hydrochloric Acid SCHEMBL6785628 | 0.66 | KDR (0.42) | KITKDRFLT3BPTFPRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686373-B2 | ANALGESICS; ANTIINFLAMMATORY AGENT | WARNER-LAMBERT COMPANY LLC | 2004-02-03 | — | — | US | disclosed |
| US-20030130277-A1 | Pyrazoloquinolinone derivatives as protein kinase C inhibitors | KAWAMURA KIYOSHI (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1310498-A2 | Pyrazoloquinolinone derivatives as protein kinase C inhibitors | PFIZER INC. (US) | 2003-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130277-A1 | Pyrazoloquinolinone derivatives as protein kinase C inhibitors | PRKCB, PRKCA, PRKCG | KIT 1665/4885KDR 3498/4885FLT3 1005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.