Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.37 |
| ▸ | TUBB4A | P04350 | 7/20 | 0.34 |
| ▸ | TUBB | P07437 | 7/20 | 0.34 |
| ▸ | TUBA3C | P0DPH7 | 7/20 | 0.34 |
| ▸ | TUBA1B | P68363 | 7/20 | 0.34 |
| ▸ | TUBA4A | P68366 | 7/20 | 0.34 |
| ▸ | TUBB4B | P68371 | 7/20 | 0.34 |
| ▸ | TUBB3 | Q13509 | 7/20 | 0.34 |
| ▸ | TUBB2A | Q13885 | 7/20 | 0.34 |
| ▸ | TUBB8 | Q3ZCM7 | 7/20 | 0.34 |
| ▸ | TUBA3E | Q6PEY2 | 7/20 | 0.34 |
| ▸ | TUBA1A | Q71U36 | 7/20 | 0.34 |
| ▸ | TUBA1C | Q9BQE3 | 7/20 | 0.34 |
| ▸ | TUBB6 | Q9BUF5 | 7/20 | 0.34 |
| ▸ | TUBB2B | Q9BVA1 | 7/20 | 0.34 |
| ▸ | TUBB1 | Q9H4B7 | 7/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6785261 | 0.82 | TUBB4A (0.38) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6786202 | 0.80 | TUBB4A (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6785029 | 0.80 | ELANE (0.43) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6785055 | 0.73 | TUBB4A (0.41) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6785181 | 0.72 | ATM (0.43) | ALDH1A1CYP1A2SMN1; SMN2 | |
| SCHEMBL6785382 | 0.71 | RXFP1 (0.47) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL902174 | 0.69 | MAOA (0.61) | PDPK1ELANEALDH1A1ADORA3CYP1A2 | |
| SCHEMBL2383365 | 0.69 | NOS1 (0.37) | ALDH1A1ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL22574703 | 0.68 | TUBB4A (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29900391 | 0.68 | TUBB4A (0.36) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686373-B2 | ANALGESICS; ANTIINFLAMMATORY AGENT | WARNER-LAMBERT COMPANY LLC | 2004-02-03 | — | — | US | disclosed |
| US-20030130277-A1 | Pyrazoloquinolinone derivatives as protein kinase C inhibitors | KAWAMURA KIYOSHI (JP) | 2003-07-10 | — | — | US | disclosed |
| EP-1310498-A2 | Pyrazoloquinolinone derivatives as protein kinase C inhibitors | PFIZER INC. (US) | 2003-05-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130277-A1 | Pyrazoloquinolinone derivatives as protein kinase C inhibitors | PRKCB, PRKCA, PRKCG | PDPK1 477/4885TUBB4A 3892/4885TUBB 3689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.