Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | DCTPP1 | Q9H773 | 5/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | XBP1 | P17861 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788315 | 0.79 | ALDH1A1 (0.36) | ALDH1A1PDE7BGRIN2DGRIN3BGRIN1 | |
| SCHEMBL6794737 | 0.68 | PDE7B (0.41) | ALDH1A1PDE7BGAAHTT | |
| SCHEMBL14018693 | 0.66 | ALDH1A1 (0.71) | ALDH1A1TSHRPGK1GAALMNA | |
| SCHEMBL3957039 | 0.63 | TSHR (0.48) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL12693888 | 0.63 | POLB (0.38) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL38662525 | 0.62 | TSHR (0.53) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL21631445 | 0.62 | MTNR1A (0.36) | ALDH1A1PDE7BGAAMAPT | |
| SCHEMBL8139921 | 0.62 | RAB9A (0.56) | ALDH1A1GAANPC1MAPTRAB9A | |
| SCHEMBL29208555 | 0.62 | SMN1; SMN2 (0.56) | ALDH1A1GAALMNANPC1MAPT | |
| SCHEMBL10393711 | 0.61 | ALDH1A1 (0.47) | ALDH1A1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029734-A1 | Fused-benzene derivatives useful as herbicides | ISHIHARA SANGYO KAISHA, LTD. | 2004-02-12 | — | — | US | disclosed |
| US-6573218-B1 | Defoliants containing such as uracil and 1,4-benzoxazole or benzthiazole moieties | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2003-06-03 | — | — | US | disclosed |
| EP-1111993-A4 | FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES | ISHIHARA SANGYO KAISHA (JP) | 2002-12-04 | — | — | EP | disclosed |
| EP-1111993-A1 | FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000013508-A1 | FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES | ISHIHARA SANGYO KAISHA, LTD. (JP) | 2000-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029734-A1 | Fused-benzene derivatives useful as herbicides | DDT, NQO2, DHRS9 | ALDH1A1 1879/4885PDE7B 4125/4885GRIN2D 148/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.