SCHEMBL6794737

SCHEMBL6794737

CCc1nc2cc(F)cc(Cl)c2o1

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PDE7B Q9NP56 3/20 0.41
GAA P10253 2/20 0.33
MTNR1A P48039 4/20 0.33
MTNR1B P49286 4/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
ALDH1A1 P00352 1/20 0.31
AKR1B1 P15121 2/20 0.31
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18325751 0.80 PDE7B (0.41) PDE7BGAAMTNR1AMTNR1BMEN1
SCHEMBL102012 0.77 ALDH1A1 (0.31) ALDH1A1
SCHEMBL14258095 0.77
SCHEMBL6794232 0.71 FBP1 (0.35) PDE7BGAA
SCHEMBL13565572 0.69 GAA (0.55) GAAMEN1KMT2A
SCHEMBL6793439 0.68 ALDH1A1 (0.39) PDE7BGAAALDH1A1HTT
SCHEMBL24821765 0.68 MTNR1A (0.38) PDE7BGAAMTNR1AMTNR1B
SCHEMBL30612624 0.67 AKR1B1 (0.43) PDE7BMEN1KMT2AALDH1A1AKR1B1
SCHEMBL30358393 0.66 AKR1B1 (0.40) PDE7BMEN1KMT2AAKR1B1
SCHEMBL2267342 0.66 ELANE (0.39) PDE7BGAAMTNR1AMTNR1BMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040029734-A1 Fused-benzene derivatives useful as herbicides ISHIHARA SANGYO KAISHA, LTD. 2004-02-12 US disclosed
US-6573218-B1 Defoliants containing such as uracil and 1,4-benzoxazole or benzthiazole moieties ISHIHARA SANGYO KAISHA, LTD. (JP) 2003-06-03 US disclosed
EP-1111993-A4 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA (JP) 2002-12-04 EP disclosed
EP-1111993-A1 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 2001-07-04 EP disclosed
WO-2000013508-A1 FUSED-BENZENE DERIVATIVES USEFUL AS HERBICIDES ISHIHARA SANGYO KAISHA, LTD. (JP) 2000-03-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040029734-A1 Fused-benzene derivatives useful as herbicides DDT, NQO2, DHRS9 PDE7B 4125/4885GAA 3233/4885MTNR1A 1475/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.