Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FPR2 | P25090 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6793606 | 0.70 | MAPKAPK2 (0.45) | ALDH1A1THRBFPR2SMN1; SMN2NAMPT | |
| SCHEMBL6800083 | 0.70 | HTR6 (0.38) | ALDH1A1THRBHTR6KMT2AMEN1 | |
| SCHEMBL6240805 | 0.69 | ALDH1A1 (0.47) | ALDH1A1KDM4ETHRBKMT2ASMN1; SMN2 | |
| SCHEMBL7093906 | 0.69 | HPGD (0.45) | KDM4ETHRBKMT2AMEN1TP53 | |
| SCHEMBL6241375 | 0.67 | WNT3A (0.49) | HTR6KMT2ASMN1; SMN2MEN1NAMPT | |
| SCHEMBL6236536 | 0.64 | MAPT (0.41) | ALDH1A1KDM4EKMT2AMEN1LMNA | |
| SCHEMBL5751507 | 0.63 | ALDH1A1 (0.75) | ALDH1A1KDM4ETHRBKMT2ASMN1; SMN2 | |
| SCHEMBL7098810 | 0.62 | DRD4 (0.35) | ALDH1A1HTR6KMT2AMEN1WNT3A | |
| SCHEMBL6260264 | 0.61 | WNT3A (0.43) | ALDH1A1KDM4EHTR6SMN1; SMN2NAMPT | |
| SCHEMBL1753925 | 0.61 | GAA (0.70) | ALDH1A1KDM4ETHRBKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030229094-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | ABBOTT LABORATORIES | 2003-12-11 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030229094-A1 | Acetamides and benzamides that are useful in treating sexual dysfunction | CATSPER1, CYP19A1, PDE12 | ALDH1A1 88/4885KDM4E 2903/4885THRB 4311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.