Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5657114 | 0.86 | OPRM1 (0.45) | CHRM2CHRM4CHRM1CHRM3OPRM1 | |
| SCHEMBL2718551 | 0.82 | LMNA (0.51) | CHRM2CHRM4CHRM1CHRM3OPRM1 | |
| SCHEMBL5204992 | 0.75 | DAO (0.47) | CHRM2CHRM4CHRM1CHRM3OPRM1 | |
| SCHEMBL7220315 | 0.69 | DAO (0.44) | CHRM2CHRM4CHRM1CHRM3OPRM1 | |
| SCHEMBL3195760 | 0.67 | HTR7 (0.48) | CHRM2CHRM1CHRM3OPRM1OPRK1 | |
| SCHEMBL23832547 | 0.66 | LMNA (0.48) | CHRM2CHRM4CHRM1CHRM3OPRM1 | |
| SCHEMBL2722132 | 0.66 | L3MBTL1 (0.49) | CHRM1OPRM1OPRK1HPGDMAPK1 | |
| SCHEMBL3195768 | 0.66 | HTR7 (0.53) | CHRM2CHRM1CHRM3OPRM1OPRK1 | |
| SCHEMBL3142425 | 0.64 | CHRM1 (0.81) | CHRM2CHRM4CHRM1CHRM3OPRM1 | |
| SCHEMBL4084782 | 0.64 | CHRM1 (0.76) | CHRM2CHRM4CHRM1CHRM3OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116435-A1 | Benzimidazol derivatives modulate chemokine receptors | ASTRAZENECA AB (SE) | 2004-06-17 | — | — | US | disclosed |