Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | APOB | P04114 | 2/20 | 0.49 |
| ▸ | MTTP | P55157 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | WDR5 | P61964 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6796230 | 0.90 | HMOX1 (0.51) | ALDH1A1PTGS1APOBMTTPSMO | |
| SCHEMBL7137493 | 0.88 | CYP19A1 (0.49) | HIF1AEPAS1CYP19A1CYP17A1CYP11B1 | |
| SCHEMBL6794124 | 0.82 | ALDH1A1 (0.53) | ALDH1A1PTGS1APOBMTTPSMO | |
| SCHEMBL6789828 | 0.81 | PTGS1 (0.58) | ALDH1A1PTGS1APOBMTTPGAA | |
| SCHEMBL6788420 | 0.80 | MTTP (0.57) | ALDH1A1APOBMTTPGAAKDR | |
| SCHEMBL6788109 | 0.80 | MTTP (0.56) | ALDH1A1PTGS1APOBMTTPGAA | |
| SCHEMBL6791269 | 0.80 | PTGS1 (0.59) | ALDH1A1PTGS1APOBMTTPGAA | |
| SCHEMBL18132582 | 0.79 | CYP19A1 (0.60) | ALDH1A1CYP19A1KDM4EMAPTCYP17A1 | |
| SCHEMBL3729112 | 0.79 | NR1H4 (0.58) | ALDH1A1PTGS1APOBMTTPSMN1; SMN2 | |
| SCHEMBL6791009 | 0.78 | TRPV1 (0.55) | ALDH1A1PTGS1APOBMTTPSMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | ALDH1A1 1427/4885HIF1A 4361/4885EPAS1 2569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.