Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CD38 | P28907 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | APOB | P04114 | 5/20 | 0.49 |
| ▸ | MTTP | P55157 | 4/20 | 0.49 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.49 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.49 |
| ▸ | ADH5 | P11766 | 1/20 | 0.48 |
| ▸ | SMO | Q99835 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132694 | 0.88 | ADH5 (0.52) | ALDH1A1CD38SMN1; SMN2ROCK1RAB9A | |
| SCHEMBL6794773 | 0.82 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2APOBMTTPTRPV1 | |
| SCHEMBL6796230 | 0.81 | HMOX1 (0.51) | ALDH1A1SMN1; SMN2APOBMTTPTRPV1 | |
| SCHEMBL3994163 | 0.80 | EPHX2 (0.61) | ALDH1A1CD38PORCNTRPV1LMNA | |
| SCHEMBL31393757 | 0.80 | CHRNB2 (0.71) | ALDH1A1SMN1; SMN2RAB9AAPOBMTTP | |
| SCHEMBL6794747 | 0.79 | PTGS1 (0.60) | ALDH1A1SMN1; SMN2RAB9AAPOBMTTP | |
| SCHEMBL6792071 | 0.79 | TRPV1 (0.78) | ALDH1A1SMN1; SMN2RAB9AAPOBMTTP | |
| SCHEMBL3892690 | 0.78 | TRPV1 (0.63) | ALDH1A1SMN1; SMN2RAB9AAPOBMTTP | |
| SCHEMBL6791178 | 0.78 | PTGS1 (0.67) | ALDH1A1SMN1; SMN2RAB9AAPOBMTTP | |
| SCHEMBL6789828 | 0.77 | PTGS1 (0.58) | ALDH1A1SMN1; SMN2RAB9AAPOBMTTP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040058903-A1 | Benzamide compounds as apo b secretion inhibitors | APOB, APOL1, SCARB1 | ALDH1A1 1427/4885CD38 3021/4885SMN1; SMN2 2504/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.