SCHEMBL6794968

SCHEMBL6794968

Cc1cc([N+](=O)[O-])ccc1NC(=O)Cc1ccccn1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.62
ALDH1A1 P00352 3/20 0.56
KMT2A Q03164 5/20 0.55
MAPT P10636 3/20 0.55
MEN1 O00255 3/20 0.55
HPGD P15428 1/20 0.55
CCR6 P51684 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
PKM P14618 1/20 0.53
LMNA P02545 3/20 0.53
HTT P42858 1/20 0.53
GAA P10253 1/20 0.52
TAS1R3 Q7RTX0 1/20 0.51
TAS1R1 Q7RTX1 1/20 0.51
TAS1R2 Q8TE23 1/20 0.51
POLB P06746 1/20 0.50
TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4033959 0.81 MAPT (0.66) L3MBTL1ALDH1A1KMT2AMAPTMEN1
SCHEMBL6795704 0.81 MAPT (0.52) ALDH1A1KMT2AMAPTMEN1HPGD
SCHEMBL6433592 0.80 KMT2A (0.65) L3MBTL1ALDH1A1KMT2AMAPTMEN1
SCHEMBL4844382 0.79 ALDH1A1 (0.70) ALDH1A1KMT2AMAPTMEN1PKM
SCHEMBL14192526 0.77 ALDH1A1 (0.73) L3MBTL1ALDH1A1KMT2AMAPTMEN1
SCHEMBL30168150 0.76 ALDH1A1 (0.67) L3MBTL1ALDH1A1KMT2AMAPTMEN1
SCHEMBL14202810 0.76 ALDH1A1 (0.67) L3MBTL1ALDH1A1KMT2AMAPTMEN1
SCHEMBL10674588 0.76 ALDH1A1 (0.67) L3MBTL1ALDH1A1KMT2AMAPTMEN1
SCHEMBL2071340 0.75 L3MBTL1 (0.81) L3MBTL1ALDH1A1KMT2AMAPTMEN1
SCHEMBL29106604 0.74 MAPT (0.66) L3MBTL1ALDH1A1KMT2AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2004-03-25 US disclosed
CN-1478077-A Benzamide compounds as APO B secretion inhibitors ����ҩƷ��ҵ��ʽ���� 2004-02-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040058903-A1 Benzamide compounds as apo b secretion inhibitors APOB, APOL1, SCARB1 L3MBTL1 1793/4885ALDH1A1 1427/4885KMT2A 2457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.